HTLV-1 viral RNA is detected rarely in plasma of HTLV-1 infected subjects

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects

Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of HTLV-associated disease and viral dynamics. A subset of 45 human T-cell lymphotropic virus type 1 (HTLV-1), 45 human T-cell lymphotropic virus ty...

Interaction of perforin and granzyme B and HTLV-1 viral factors is associated with ATL development

Objective(s): Human T cell leukaemia virus type 1 (HTLV-1) is associated with adult T cell leukaemia (ATL), a malignant lymphoproliferative disease that infects CD4 T cells. It is not clear why the majority of HTLV-1-infected individuals remain asymptomatic carries (ACs) and a minority develop ATL. Cellular immune response has a critical role in ATL and destroys malign...

HTLV-1 virus detected in Nunavut.

Reduction of human T-cell leukemia virus type 1 (HTLV-1) proviral loads in rats orally infected with HTLV-1 by reimmunization with HTLV-1-infected cells.

Human T-cell leukemia virus type 1 (HTLV-1) persistently infects humans, and the proviral loads that persist in vivo vary widely among individuals. Elevation in the proviral load is associated with serious HTLV-1-mediated diseases, such as adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. However, it remains controversial whether HTLV-1-specific T-cell immunit...

تظاهرات چشمی HTLV-1

چکیده عفونت با ویروس سلول T لنفوتروپیک انسانی( HTLV-1 ) در برخی از مناطق دنیا اندمیک م یباشد که یکی از مناطق شیوع آن در خراسان م یباشد. یکی از درگیری های این ویروس درگیری چشمی م یباشد. تظاهرات شناخته شده چشمی این ویروس شامل انفیلتراسیون بدخیمی در بیماران با لوکمی /لنفوم T سل بالغین، دژنراسیون شبکیه، درگیری نوروافتالمیک، واسکولیت و اگزودا در پریفر شبکیه، کراتو کونژکتویت سیکا - به خصوص در بیماران...